New York State health officials have confirmed the first case of a new mpox strain, clade Ib, in an individual recently returned from Africa. While the public risk remains low, authorities emphasize the importance of vaccination and prevention.
New mpox strain confirmed in NY for the first time

Key Takeaways:
- New mpox strain clade Ib confirmed in New York State.
- Infected individual traveled from Africa and is in isolation.
- No known local transmission; public risk remains low.
- JYNNEOS vaccine expected to be effective against the new strain.
- Health officials urge vaccination and preventive measures.
New Strain Emerges in New York
The New York State Department of Health has issued a health advisory following the confirmation of the first case of mpox clade Ib in the state. The infected individual, who exhibited symptoms, had recently traveled from Africa and is currently under medical care.
Infected Individual Isolated
State Health Commissioner Dr. James McDonald stated that the patient is being cared for by a physician and is in isolation “until the full resolution of symptoms.” He emphasized, “There is no known local transmission of mpox clade Ib in the community where the individual lives or anywhere within New York State.”
Public Risk Remains Low
Health officials assure the public that the risk remains low, with no additional known community cases of this strain in New York State at this time. The Department of Health continues to monitor the situation closely and maintain precautionary measures.
Vaccination Encouraged
Dr. McDonald highlighted that the JYNNEOS vaccine, a two-dose preventative series for mpox, is “expected to be effective” against this new strain. “[It is] available for individuals at risk with the standing order I signed last year,” he noted. “There is no immediate risk to the general public.”
Understanding Mpox Transmission and Symptoms
Mpox, formerly known as monkeypox, is “rarely fatal,” according to the health department. However, it can be dangerous for people with immunocompromising conditions, older adults, young children, and pregnant women. Symptoms often include rashes that progress to “painful skin lesions,” swollen lymph nodes, fever, sore throat, headaches, back pain, low energy, and muscle aches.
The department stressed that there is a “high likelihood of transmission” until lesions scab over, urging infected individuals to isolate until new skin forms at the lesion sites. Mpox spreads through close, intimate contact with sores, scabs, or rashes, as well as through respiratory droplets, saliva, or mucus from an infected person.
Global Context of Mpox Clade Ib
Dr. Myles Druckman, global medical director at International SOS in California, reported that several countries in Central and Eastern Africa have observed this strain. “We’re finding that other countries have also reported travel-associated cases of clade I, including Belgium, Canada, China, France, Germany, India, Ireland, Oman, Pakistan, South Sudan, Sweden, Thailand, the United Kingdom, and Zimbabwe,” he said.
“It’s important to recognize that cases of this strain are expected due to the ongoing outbreak in multiple countries and the risks associated with global travel,” Dr. Druckman added.
Prevention Measures and Recommendations
Health experts recommend vaccination for high-risk individuals, such as healthcare workers with high exposure and people with weakened immune systems. “Prevention of mpox is mainly through vaccination and avoiding skin-to-skin contact with others—especially those with symptoms or visible outbreaks—and observing good personal hygiene and washing hands well and frequently,” Dr. Druckman advised.
Those planning to travel to areas with reported cases of mpox are encouraged to consider vaccination with the two doses of JYNNEOS. The health department advises individuals to inquire with local pharmacies or healthcare providers about vaccine availability.
Continued Vigilance Urged
As authorities monitor and maintain the situation, the emphasis remains on prevention and awareness to mitigate the spread of the new mpox strain. The public is encouraged to stay informed and follow health guidelines to protect themselves and others.