No. 6 Oregon travels to No. 3 Penn State in a blockbuster Top 25 clash headlining Week 5 of college football. With four marquee showdowns among ranked teams and at least six more intriguing matchups on the schedule, fans can expect a pivotal weekend that could reshape the national landscape.
No. 6 Oregon at No. 3 Penn State is the main event on an attractive Top 25 schedule

Key Takeaways:
- No. 6 Oregon at No. 3 Penn State is the main event.
- Four AP Top 25 matchups anchor Week 5 of the college football schedule.
- At least six additional games featuring ranked teams add to the weekend’s intrigue.
- ERIC OLSON of the Associated Press provided the original report.
- Herald & Review published the story on September 27, 2025.
The Spotlight: Oregon at Penn State
No. 6 Oregon’s trip to face No. 3 Penn State stands out as the must-watch contest of Week 5. This high-profile matchup features two of the nation’s top-ranked programs, setting the tone for a weekend loaded with potential playoff implications. Fans will be paying close attention to the on-field strategies and heightened atmosphere that accompany a showdown at this level.
Four Top 25 Matchups
Headlining the Week 5 schedule are four total showdowns between AP Top 25 teams. While Oregon and Penn State lead the charge in popularity and ranking, other ranked clashes are generating their own excitement. Each of these games carries the potential to shake up conference standings and national positioning heading into the mid-season stretch.
Additional Ranked Contenders
Beyond the marquee pairings, at least a half-dozen games involving ranked teams are drawing nearly as much attention. Though specifics on these matchups are limited, they underscore the depth of the competition in NCAA Division I FBS football. Observers anticipate several of these contests could produce surprises, upsets, or breakout performances from rising stars.
Perspective from the Field
Eric Olson of the Associated Press frames this collective slate of marquee and under-the-radar ranked games as one of the most intriguing weekends of the season. Published by the Herald & Review, this outlook emphasizes how Week 5 can shape major conference races, from the Big Ten to the Southeastern Conference, and beyond. As the season progresses, the action unfolding this weekend may provide a clearer picture of which teams truly have championship potential.